Biochem/physiol Actions

Reversible: yes

Product competes with ATP.

Primary TargetPKC

Target IC₅₀: 2.45 µM against protein kinase C

Cell permeable: yes

General description

A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (IC₅₀ = 2.45 µM) and protein kinase A (IC₅₀ = 25.7 µM).

A cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (IC₅₀ = 25.7 µM) and protein kinase C (IC₅₀ = 2.45 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Fabre, S., et al. 1993. Bioorg. Med. Chem.1, 193.Nakanishi, S., et al. 1986. J. Antibiot. 39, 1066.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Warning

Toxicity: Standard Handling (A)